Methionine transsulfuration pathway is upregulated in long-lived humans. |
2021 |
Mota Martorell, N.; Jove, M.; Borras, C.; Berdun, R.; Obis, E.; Sol, J.; Cabre, R.; Pradas, I.; Galo Licona, J.D.; Puig, J.; Viña, J.; Pamplona, R. |
Article d'investigació |
Lipid alterations in human frontal cortex in ALS-FTLD-TDP43 proteinopathy spectrum are partially related to peroxisome impairment |
2020 |
Andres Benito, P.; Gelpi, E.; Jove, M.; Mota Martorell, N.; Obis, E.; Portero Otin, M.; Povedano, M.; Pujol, A.; Pamplona, R.; Ferrer, I. |
Article d'investigació |
Sixty years-old is the breakpoint of the human frontal cortex aging. |
2017 |
Cabré R; Naudí A; Dominguez-Gonzalez M; Ayala V; Jové M; Mota-Martorell N; Piñol-Ripoll G;Gil-Villar MP; Rué M; Portero-Otín M; Ferrer I; Pamplona R |
Article d'investigació |
Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system |
2017 |
Naudí A, Cabré R, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R. |
Article d'investigació |
Specific metabolomics adaptations define a differential regional vulnerability in the adult human cerebral cortex |
2016 |
Cabré R; Jové M; Naudí A; Ayala V; Piñol-Ripoll G; Gil-Villar MP; Dominguez-Gonzalez M; Obis E; Berdun R; Mota-Martorell N; Portero-Otin M; Ferrer I; Pamplona R. |
Article d'investigació |
Human Aging Is a Metabolome-related Matter of Gender |
2016 |
Jové M, Maté I, Naudí A, Mota-Martorell N, Portero-Otín M, De la Fuente M, Pamplona R. |
Article d'investigació |
Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autopha |
2016 |
Martínez-Cisuelo V, Gómez J, García-Junceda I, Naudí A, Cabré R, Mota-Martorell N, López-Torres M, González-Sánchez M, Pamplona R, Barja G. |
Article d'investigació |
Cysteine dietary supplementation reverses the decrease in mitochondrial ROS production at complex I induced by methionine restriction |
2015 |
Gomez, A; Gomez, J; Lopez Torres, M; Naudí, A; Mota-Martorell, N; Pamplona, R; Barja, G. |
Article d'investigació |